Synthesis of Functionalized Indenes via Cascade Reaction of Aziridines and Propargyl Alcohols

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• 作者：Shaoyin Wang ; Yuanxun Zhu ; Yanguang Wang ; Ping Lu
• 刊名：Organic Letters
• 出版年：2009
• 出版时间：June 18, 2009
• 年：2009
• 卷：11
• 期：12
• 页码：2615-2618
• 全文大小：166K
• 年卷期：v.11,no.12(June 18, 2009)
• ISSN：1523-7052

文摘

A concise synthesis of functionalized indenes via the Lewis acid catalyzed cascade reaction of aziridines and propargylic alcohols has been developed. The methodology offers great potential for the synthesis of biologically active indene derivatives and related polycyclic compounds.