Strategy for the Resolution of a Chiral Dearomatization Agent:{TpRe(CO)(1-methylimidazole)} Coordination of -Pinene (Tp = Hyd

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• 作者：Scott H. Meiere ; Mark T. Valahovic ; and W. Dean Harman
• 刊名：Journal of the American Chemical Society
• 出版年：2002
• 出版时间：December 18, 2002
• 年：2002
• 卷：124
• 期：50
• 页码：15099 - 15103
• 全文大小：128K
• 年卷期：v.124,no.50(December 18, 2002)
• ISSN：1520-5126

文摘

A methodology for resolving TpRe(CO)(1-methylimidazole)(hars/eta.gif" BORDER=0 >²-benzene) has been developedutilizing (R)-hars/alpha.gif" BORDER=0>-pinene. Each enantiomer of the {TpRe(CO)(MeIm)} system can be obtained with theenantiomer ratio (er) = 97:3 by taking advantage of differing rates of pinene substitution for the twodiastereomers of TpRe(CO)(MeIm)(hars/eta.gif" BORDER=0 >²-(R)-hars/alpha.gif" BORDER=0>-pinene).