We demonstrate very high frequency (VHF) nanomechanical resonators based upon single-crystal silicon nanowires (SiNWs), which are preparedby t
he bottom-up c
hemical synt
hesis. Metallized SiNW resonators operating near 200 MHz are realized with quality factor
Q 2000-2500.Pristine SiNWs, with fundamental resonances as high as 215 MHz, are measured using a VHF readout technique that is optimized for t
hesehigh resistance devices. T
he pristine resonators provide t
he hig
hest
Q's, as high as
Q 13 100 for an 80 MHz device. SiNWs excel at masssensing; characterization of t
heir mass responsivity and frequency stability demonstrates sensitivities approaching 10 zeptograms. T
heseSiNW resonators offer significant potential for applications in resonant sensing, quantum electromechanical systems, and high frequencysignal processing.