One-Pot Iodination of Hydroxypyridines

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• 作者：Kevin M. Maloney ; Emily Nwakpuda ; Jeffrey T. Kuethe ; Jingjun Yin
• 刊名：Journal of Organic Chemistry
• 出版年：2009
• 出版时间：July 17, 2009
• 年：2009
• 卷：74
• 期：14
• 页码：5111-5114
• 全文大小：160K
• 年卷期：v.74,no.14(July 17, 2009)
• ISSN：1520-6904

文摘

A one-pot, high-yielding iodination of hydroxypyridines and hydroxyquinolines is described. The iodination proceeds under mild conditions, and the products are obtained in high yield without the need for chromatographic purification. In addition, the iodination works on both 2- and 4-hydroxypyridines and -hydroxyquinolines.