A Microwave-Assisted Diastereoselective Multicomponent Reaction To Access Dibenzo[c,e]azepinones: Synthesis and Biological Evaluation

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• 作者：Vaibhav P. Mehta ; Sachin G. Modha ; Eelco Ruijter ; Kristof Van Hecke ; Luc Van Meervelt ; Christophe Pannecouque ; Jan Balzarini ; Romano V. A. Orru ; Erik Van der Eycken
• 刊名：Journal of Organic Chemistry
• 出版年：2011
• 出版时间：April 15, 2011
• 年：2011
• 卷：76
• 期：8
• 页码：2828-2839
• 全文大小：1171K
• 年卷期：v.76,no.8(April 15, 2011)
• ISSN：1520-6904

文摘

An unprecedented microwave-assisted multicomponent strategy has been elaborated for the fast, efficient, and diastereoselective generation of the dibenzo[c,e]azepinone scaffold. The generated compounds were evaluated for their bioactivity.