Nickel-Catalyzed Cross-Coupling of Aryl Phosphates with Arylboronic Acids

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• 作者：Hu Chen ; Zhongbin Huang ; Xiaoming Hu ; Guo Tang ; Pengxiang Xu ; Yufen Zhao ; Chien-Hong Cheng
• 刊名：Journal of Organic Chemistry
• 出版年：2011
• 出版时间：April 1, 2011
• 年：2011
• 卷：76
• 期：7
• 页码：2338-2344
• 全文大小：934K
• 年卷期：v.76,no.7(April 1, 2011)
• ISSN：1520-6904

文摘

The Suzuki鈭扢iyaura cross-coupling of aryl phosphates using Ni(PCy₃)₂Cl₂ as an inexpensive, bench-stable catalyst is described. Broad substrate scope and high efficiency are demonstrated by the syntheses of more than 40 biaryls and by constructing complex organic molecules. The poor reactivity of aryl phosphates relative to aryl halides is successfully employed to construct polyarenes by selective cross-coupling using Pd and Ni catalysts.