Synergistic Antibacterial Brilliant Blue/Reduced Graphene Oxide/Quaternary Phosphonium Salt Composite with Excellent Water Solubility and Specific Targeting Capability

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• 作者：Xiang Cai ; Shaozao Tan ; Minsong Lin ; Agui Xie ; Wenjie Mai ; Xiuju Zhang ; Zhidan Lin ; Ting Wu ; Yingliang Liu
• 刊名：Langmuir
• 出版年：2011
• 出版时间：June 21, 2011
• 年：2011
• 卷：27
• 期：12
• 页码：7828-7835
• 全文大小：1072K
• 年卷期：v.27,no.12(June 21, 2011)
• ISSN：1520-5827

文摘

A water-soluble brilliant blue/reduced graphene oxide/tetradecyltriphenylphosphonium bromide composite (BB-rGO-TTP) was prepared by using noncovalent brilliant blue-functionalized reduced graphene oxide (BB-rGO) as the tetradecyltriphenylphosphonium bromide (TTP) carrier. Antibacterial performance of this novel composite was investigated for both Gram-positive and Gram-negative bacteria. The results showed that the novel BB-rGO-TTP, combing the advantages of graphene and TTP, displayed excellent synergistic antibacterial activity, specific targeting capability, water solubility, and mild cytotoxicity, suggesting the great potential application as sprayable graphene-based antibacterial solutions.