Observation of Binuclear Palladium Clusters upon ESI-MS Monitoring of the Suzuki鈥揗iyaura Cross-Coupling Catalyzed by a Dichloro-bis(aminophosphine) Complex of Palladium

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• 作者：Divya Agrawal ; Detlef Schro虉der ; Christian M. Frech
• 刊名：Organometallics
• 出版年：2011
• 出版时间：July 11, 2011
• 年：2011
• 卷：30
• 期：13
• 页码：3579-3587
• 全文大小：976K
• 年卷期：v.30,no.13(July 11, 2011)
• ISSN：1520-6041

文摘

Electrospray ionization mass spectrometry (ESI-MS) is used for monitoring the progress of the Suzuki鈥揗iyaura cross-coupling reaction between bromobenzene and arylboronic acids using a palladium dichloro-bis(aminophosphine) complex as a precatalyst. The ESI-MS studies demonstrate that initiation of the catalytic reaction requires the presence of a base and that the selectivity for cross-coupling is favorable at elevated temperatures. Interestingly, after completion of the coupling reaction, the palladium is present as a dinuclear Pd⁰/Pd^II cluster, which still acts as an active catalyst when a new aliquot of reactants is added to the reaction mixture.