Metal-Free TEMPO-Promoted C(sp3)鈥揌 Amination To Afford Multisubstituted Benzimidazoles

详细信息    查看全文

• 作者：Ding Xue ; Ya-Qiu Long
• 刊名：Journal of Organic Chemistry
• 出版年：2014
• 出版时间：May 16, 2014
• 年：2014
• 卷：79
• 期：10
• 页码：4727-4734
• 全文大小：421K
• 年卷期：v.79,no.10(May 16, 2014)
• ISSN：1520-6904

文摘

An efficient TEMPO鈥揳ir/cat. TEMPO鈥揙₂ oxidative protocol was developed to synthesize multisubstituted or fused tetracyclic benzimidazoles via a metal-free oxidative C鈥揘 coupling between the sp³ C鈥揌 and free N鈥揌 of readily available N¹-benzyl/alkyl-1,2-phenylenediamines.