Designing Tetrahydroimidazo[1,2-a]pyridine Derivatives via Catalyst-free Aza-Diels−Alder Reaction (ADAR) and Their Insecticidal Evaluation

详细信息    查看全文

• 作者：Wenwen Zhang ; Yinbo Chen ; Weidong Chen ; Zewen Liu ; Zhong Li
• 刊名：Journal of Agricultural and Food Chemistry
• 出版年：2010
• 出版时间：May 26, 2010
• 年：2010
• 卷：58
• 期：10
• 页码：6296-6299
• 全文大小：734K
• 年卷期：v.58,no.10(May 26, 2010)
• ISSN：1520-5118

文摘

A series of tetrahydroimidazo[1,2-a]pyridine derivatives were synthesized by the reaction of 2-vinyl-4,5-dihydroimidazole derivatives with substituted benzylidenemalononitrile via a catalyst-free aza-Diels−Alder reaction. Insecticidal activities of target compounds were tested against pea aphids (Aphis craccivora), which showed that activities were strongly influenced by the substituents and their positions. Especially, the introduction of a fluoro group at the 2- position increased activities.