Pd(II)-Catalyzed Synthesis of Carbolines by Iminoannulation of Internal Alkynes via Direct C−H Bond Cleavage Using Dioxygen as Oxidant

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• 作者：Shengtao Ding ; Zhuangzhi Shi ; Ning Jiao
• 刊名：Organic Letters
• 出版年：2010
• 出版时间：April 2, 2010
• 年：2010
• 卷：12
• 期：7
• 页码：1540-1543
• 全文大小：261K
• 年卷期：v.12,no.7(April 2, 2010)
• ISSN：1523-7052

文摘

A palladium-catalyzed iminoannulation of internal alkynes via direct C−H bond cleavage was developed. Dioxygen was employed as a clean oxidant in this kind of catalysis. Carbolines were synthesized from tert-butylimines of N-substituted indole-2-carboxaldehydes or indole-3-carboxaldehydes.