Kinetic Study on the Enzymatic Resolution of Homophenylalanine Ester Using Ionic Liquids

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• 作者：Hua Zhao ; Robert G. Luo ; and Sanjay V. Malhotra
• 刊名：Biotechnology Progress
• 出版年：2003
• 出版时间：June 2003
• 年：2003
• 卷：19
• 期：3
• 页码：1016 - 1018
• 全文大小：71K
• 年卷期：v.19,no.3(June 2003)
• ISSN：1520-6033

文摘

Two ionic liquids (ILs) were investigated as novel media for the enzymatic resolutionof amino acid ester to obtain enantiomeric amino acid homophenylalanine. The effectsof solvent nature, polarity, and concentration on the kinetic resolution were investigated. With change in solvent concentration, a systematic study shows that animproved enzyme activity can be obtained by adjusting these solvent parameters.