Electronic Fingerprints of DNA Bases on Graphene

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• 作者：Towfiq Ahmed ; Svetlana Kilina ; Tanmoy Das ; Jason T. Haraldsen ; John J. Rehr ; Alexander V. Balatsky
• 刊名：Nano Letters
• 出版年：2012
• 出版时间：February 8, 2012
• 年：2012
• 卷：12
• 期：2
• 页码：927-931
• 全文大小：308K
• 年卷期：v.12,no.2(February 8, 2012)
• ISSN：1530-6992

文摘

We calculate the electronic local density of states (LDOS) of DNA nucleotide bases (A,C,G,T), deposited on graphene. We observe significant base-dependent features in the LDOS in an energy range within a few electronvolts of the Fermi level. These features can serve as electronic fingerprints for the identification of individual bases in scanning tunneling spectroscopy (STS) experiments that perform image and site dependent spectroscopy on biomolecules. Thus the fingerprints of DNA-graphene hybrid structures may provide an alternative route to DNA sequencing using STS.

Keywords:

STM; electronic DNA sequencing; graphene; tunneling conductance; DNA base fingerprints