Facile Synthesis of 3a,6a-Dihydro-furo[2,3-b]furans and Polysubstituted Furans Involving Dearomatization of Furan Ring via Electrocyclic Ring-Closure

详细信息    查看全文

• 作者：Biaolin Yin ; Guohui Zeng ; Congbi Cai ; Fanghua Ji ; Li Huang ; Zhengrong Li ; Huanfeng Jiang
• 刊名：Organic Letters
• 出版年：2012
• 出版时间：January 20, 2012
• 年：2012
• 卷：14
• 期：2
• 页码：616-619
• 全文大小：340K
• 年卷期：v.14,no.2(January 20, 2012)
• ISSN：1523-7052

文摘

A facile and atom-economic method for the synthesis of 3a,6a-dihydro-furo[2,3-b]furan derivatives and polysubstituted furans starting from furylcarbionls has been developed. This protocol involved a domino Claisen rearrangement/dearomatizing electrocyclic ring-closure/aromatizing electrocyclic ring-opening sequence.