Rh(I)-Catalyzed Insertion of Allenes into C–C Bonds of Benzocyclobutenols

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• 作者：Chunliang Zhao ; Li-Chuan Liu ; Jing Wang ; Chenran Jiang ; Qing-Wei Zhang ; Wei He
• 刊名：Organic Letters
• 出版年：2016
• 出版时间：January 15, 2016
• 年：2016
• 卷：18
• 期：2
• 页码：328-331
• 全文大小：330K
• ISSN：1523-7052

文摘

Herein we report a Rh(I)-catalyzed two carbon insertion into C–C bonds of benzocyclobutenols by employing symmetrical and unsymmetrical allenes. This reaction provides rapid access to alkylidene tetralins bearing two adjacent stereogenic centers in good yields and diasteroselectivities.