Cu(II)-Promoted Transformations of 伪-Thienylcarbinols into Spirothienooxindoles: Regioselective Halogenation of Dienyl Sulfethers Containing Electron-Rich Aryl Rings

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• 作者：Biaolin Yin ; Li Huang ; Xiaoyu Zhang ; Fanghua Ji ; Huanfeng Jiang
• 刊名：The Journal of Organic Chemistry
• 出版年：2012
• 出版时间：July 20, 2012
• 年：2012
• 卷：77
• 期：14
• 页码：6365-6370
• 全文大小：342K
• 年卷期：v.77,no.14(July 20, 2012)
• ISSN：1520-6904

文摘

Under the promotion of Cu(II) salts, the 伪-thienylcarbinols with an N-phenyl carbonyl group at the other 伪-position are converted into three different ranges of spirothienooxindoles involving dearomatizing Friedel鈥揅rafts reaction. In addition, the unprecedented regioselective CuX₂-mediated C鈥揌 functionalization/halogenation of dienyl sulfether containing electron-rich aryl rings is presented.