Three-Hindered Quadrant Phosphine Ligands with an Aromatic Ring Backbone for the Rhodium-Catalyzed Asymmetric Hydrogenation of Functionalized Alkenes

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• 作者：Zhenfeng Zhang ; Ken Tamura ; Daisuke Mayama ; Masashi Sugiya ; Tsuneo Imamoto
• 刊名：The Journal of Organic Chemistry
• 出版年：2012
• 出版时间：April 20, 2012
• 年：2012
• 卷：77
• 期：8
• 页码：4184-4188
• 全文大小：240K
• 年卷期：v.77,no.8(April 20, 2012)
• ISSN：1520-6904

文摘

The three-hindered quadrant phosphine ligands (R)-1-tert-butylmethylphosphino-2-(di-tert-butylphosphino)benzene ((R)-3H-BenzP*) and (R)-2-tert-butylmethylphosphino-3-(di-tert-butylphosphino)quinoxaline ((R)-3H-QuinoxP*) exhibited good to excellent enantioselectivities in the rhodium-catalyzed asymmetric hydrogenation of selected dehydroamino acid derivatives, enamides, and ethenephosphonates.