Geminal Alkene鈥揂lkyne Cross Metathesis Using a Relay Strategy

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• 作者：Joseph R. Clark ; Jonathan M. French ; Edgars Jecs ; Steven T. Diver
• 刊名：Organic Letters
• 出版年：2012
• 出版时间：August 17, 2012
• 年：2012
• 卷：14
• 期：16
• 页码：4178-4181
• 全文大小：262K
• 年卷期：v.14,no.16(August 17, 2012)
• ISSN：1523-7052

文摘

A relay strategy was employed to achieve an intermolecular ene鈥搚ne metathesis between 1,1-disubstituted alkenes and alkynes. The relay serves to activate an unreactive alkene which will not participate in ene-yne metathesis. The new relay cross ene鈥搚ne metathesis gives rise to 1,1,3-trisubstituted-1,3-dienes previously inaccessible by direct ene鈥搚ne metathesis methods.