Selective Detection of Iodide and Cyanide Anions Using Gold-Nanoparticle-Based Fluorescent Probes

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• 作者：Shih-Chun Wei ; Pang-Hung Hsu ; Yen-Fei Lee ; Yang-Wei Lin ; Chih-Ching Huang
• 刊名：ACS Applied Materials & Interfaces
• 出版年：2012
• 出版时间：May 23, 2012
• 年：2012
• 卷：4
• 期：5
• 页码：2652-2658
• 全文大小：344K
• 年卷期：v.4,no.5(May 23, 2012)
• ISSN：1944-8252

文摘

We developed two simple, rapid, and cost-effective fluorescent nanosensors, both featuring bovine serum albumin labeled with fluorescein isothiocyanate (FITC))-capped gold nanoparticles (FITC鈥揃SA鈥揂u NPs), for the selective sensing of cyanide (CN鈥?/sup>) and iodine (I鈥?/sup>) ions in high-salinity solutions and edible salt samples. During the preparation of FITC鈥揃SA鈥揂u NP probes, when AuNPs were introduced to the mixture containing FITC and BSA, the unconjugated FITC and FITC-labeled BSA (FITC鈥揃SA) adsorbed to the particles鈥?surfaces. These probes operated on a basic principle that I鈥?/sup> and CN鈥?/sup> deposited on the surfaces of the Au NPs or the etching of Au NPs induced the release of FITC molecules or FITC鈥揃SA into the solution, and thus restored the florescence of FITC. We employed FITC鈥揃SA to protect the Au NPs from significant aggregation in high-salinity solutions. In the presence of masking agents such as S₂O₈2鈥?/sup>/Pb²⁺, FITC鈥揃SA鈥揂u NPs facilitated the selective detection of CN鈥?/sup> (by at least 150-fold in comparison with other anions). We also demonstrated that the FITC鈥揃SA鈥揂u NPs in the presence of H₂O₂ could selectively detect I鈥?/sup> down to 50 nM. Taking advantages of their high stability and selectivity, we employed our FITC鈥揃SA鈥揂u NP-based probes for the detection of CN鈥?/sup> and I鈥?/sup> in water samples (pond water, tap water, and seawater) and detection of I鈥?/sup> in edible salt samples, respectively. This simple, rapid, and cost-effective sensing system appears to demonstrate immense practical potential for the detection of anions in real samples.

Keywords:

cyanide; iodide; gold nanoparticles; fluorescence detection; edible salt