Silver-Mediated Trifluoromethylation of Aryldiazonium Salts: Conversion of Amino Group into Trifluoromethyl Group

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• 作者：Xi Wang ; Yan Xu ; Fanyang Mo ; Guojing Ji ; Di Qiu ; Jiajie Feng ; Yuxuan Ye ; Songnan Zhang ; Yan Zhang ; Jianbo Wang
• 刊名：The Journal of the American Chemical Society
• 出版年：2013
• 出版时间：July 17, 2013
• 年：2013
• 卷：135
• 期：28
• 页码：10330-10333
• 全文大小：341K
• 年卷期：v.135,no.28(July 17, 2013)
• ISSN：1520-5126

文摘

A novel strategy for aromatic trifluoromethylation by converting aromatic amino group into CF₃ group is reported herein. This method, which can be considered as trifluoromethylation variation of the classic Sandmeyer reaction, uses readily available aromatic amines as starting materials and is performed under mild conditions.