Determination and Correlation of Solubility Data and Dissolution Thermodynamic Data of l-Lactide in Different Pure Solvents

详细信息    查看全文

• 作者：Zhen Chen ; Chuang Xie ; Zhao Xu ; Yongli Wang ; Haiping Zhao ; Hongxun Hao
• 刊名：Journal of Chemical & Engineering Data
• 出版年：2013
• 出版时间：January 10, 2013
• 年：2013
• 卷：58
• 期：1
• 页码：143-150
• 全文大小：298K
• 年卷期：v.58,no.1(January 10, 2013)
• ISSN：1520-5134

文摘

The solubility of l-lactide in pure ethanol, ethyl acetate, acetone, isopropanol, methanol, and methylbenzene from (278.15 to 338.15) K was determined by dynamic method with a laser monitoring technique. It was found that l-lactide is sparingly soluble in ethanol, isopropanol, methanol, and methylbenzene while it has high solubility in ethyl acetate and acetone. The solubility data of l-lactide in different solvents increase with the increasing of temperature. The measured solubility data of l-lactide were correlated by using the modified Apelblat, Wilson, nonrandom two-liquid (NRTL), and universal quasichemical (UNIQUAC) models, respectively. It was found that NRTL equations give the best correlation results for most solvents except for ethanol. The dissolution enthalpy, entropy of l-lactide, and the free Gibbs energy change of l-lactide in these solvents were obtained by using the van鈥檛 Hoff equation. From solubility data, melting point, fusion enthalpy, and entropy of l-lactide and d-lactide, it was proven that the thermodynamic data of d-lactide are the same with those data of l-lactide.