Sulfur(IV)-Mediated Transformations: From Ylide Transfer to Metal-Free Arylation of Carbonyl Compounds

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• 作者：Xueliang Huang ; Mahendra Patil ; Christophe Far猫s ; Walter Thiel ; Nuno Maulide
• 刊名：The Journal of the American Chemical Society
• 出版年：2013
• 出版时间：May 15, 2013
• 年：2013
• 卷：135
• 期：19
• 页码：7312-7323
• 全文大小：735K
• 年卷期：v.135,no.19(May 15, 2013)
• ISSN：1520-5126

文摘

The development of a direct ylide transfer to carbonyl derivatives and of a sulfoxide-mediated arylation is presented from a unified perspective. Mechanistic studies (including density functional calculations) support a common reaction pathway and showcase how subtle changes in reactant properties can lead to disparate and seemingly unrelated reaction outcomes.