Direct Benzothiophene Formation via Oxygen-Triggered Intermolecular Cyclization of Thiophenols and Alkynes Assisted by Manganese/PhCOOH

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• 作者：Kaisheng Liu ; Fan Jia ; Hui Xi ; Yuanming Li ; Xiaojian Zheng ; Qiaoxia Guo ; Baojian Shen ; Zhiping Li
• 刊名：Organic Letters
• 出版年：2013
• 出版时间：April 19, 2013
• 年：2013
• 卷：15
• 期：8
• 页码：2026-2029
• 全文大小：336K
• 年卷期：v.15,no.8(April 19, 2013)
• ISSN：1523-7052

文摘

An intermolecular oxidative cyclization between thiophenols and alkynes for benzothiophene formation has been established. A variety of multifunctional benzothiophenes are synthesized. In addition, we demonstrated that the obtained benzothiophenes can be used for further transformation to give diverse benzothiophene derivatives efficiently and selectively.