Dual Selectivity: Electrophile and Nucleophile Selective Cross-Coupling Reactions on a Single Aromatic Substrate

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• 作者：Annika C. J. Heinrich ; Birk Thiedemann ; Paul J. Gates ; Anne Staubitz
• 刊名：Organic Letters
• 出版年：2013
• 出版时间：September 20, 2013
• 年：2013
• 卷：15
• 期：18
• 页码：4666-4669
• 全文大小：265K
• 年卷期：v.15,no.18(September 20, 2013)
• ISSN：1523-7052

文摘

The development of a high yielding, both nucleophile and electrophile selective cross-coupling reaction with aromatic rings is presented. The reaction is general with respect to functional groups. Furthermore, the products still contain a boronic ester and a bromide. These two functional groups allow them to be easy-to-prepare, highly complex starting materials for further reactions, avoiding protecting group transformations.