Silyl Migrations in d-Xylose Derivatives: Total Synthesis of a Marine Quinoline Alkaloid

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• 作者：Anuchit Phanumartwiwath ; Thomas W. Hornsby ; Joazaizulfazli Jamalis ; Christopher D. Bailey ; Christine L. Willis
• 刊名：Organic Letters
• 出版年：2013
• 出版时间：November 15, 2013
• 年：2013
• 卷：15
• 期：22
• 页码：5734-5737
• 全文大小：259K
• 年卷期：v.15,no.22(November 15, 2013)
• ISSN：1523-7052

文摘

A versatile method for the synthesis of orthogonally protected d-xylose 1-thioethers is described using unusual silyl group migrations which were pivotal in the synthesis of 4,8-dimethyl-6-O-(2鈥?4鈥?di-O-methyl-尾-d-xylopyranosyl)hydroxyquinoline confirming the structure and absolute configuration of the natural product.