Bioactive Hybrid Organogels Based on Miniemulsion Synthesis of Morphologically Complex Polymer/Surfactant/Calcium Phosphate Nanostructures

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• 作者：Khrongkhwan Akkarachaneeyakorn ; Mei Li ; Joe Harris ; Sean A. Davis ; Stephen Mann
• 刊名：Chemistry of Materials
• 出版年：2014
• 出版时间：October 28, 2014
• 年：2014
• 卷：26
• 期：20
• 页码：5965-5972
• 全文大小：526K
• ISSN：1520-5002

文摘

Morphologically complex amorphous calcium phosphate nanostructures are synthesized within supersaturated water-in-oil miniemulsions stabilized by a mixture of a calcium bis(2-ethylhexyl)phosphate (Ca(DEHP)₂) surfactant and poly(ethylene oxide)₁₉-poly(propylene oxide)₆₉-poly(ethylene oxide)₁₉ (P123) triblock copolymer. Solvent evaporation at room temperature results in self-supporting viscous organogels comprising an interconnected network of calcium phosphate nanofilaments embedded within a continuous polymer/surfactant matrix. The P123/DEHP/calcium phosphate organogels are employed as a bioactive filler for the occlusion of exposed dentine tubules using a standard bovine tooth model.