Panorama is a web application for storin
g, sharin
g, analyzin
g, and reusin
g tar
geted assays created and refined with Skyline,1 an increasin
gly popular Windows client software tool for tar
geted proteomics experiments. Panorama allows laboratories to store and or
ganize curated results contained in Skyline documents with fine-
grained permissions, which facilitates distributed collaboration and secure sharin
g of published and unpublished data via a web-browser interface. It is fully inte
grated with the Skyline workflow and supports publishin
g a document directly to a Panorama server from the Skyline user interface. Panorama captures the complete Skyline document information content in a relational database schema. Curated results published to Panorama can be a
ggre
gated and exported as chromato
gram libraries. These libraries can be used in Skyline to pick optimal tar
gets in new experiments and to validate peak identification of tar
get peptides. Panorama is open-source and freely available. It is distributed as part of LabKey Server,2 an open source biomedical research data mana
gement system. Laboratories and or
ganizations can set up Panorama locally by downloadin
g and installin
g the software on their own servers. They can also request freely hosted projects on
g" class="extLink">https://panoramaweb.org, a Panorama server maintained by the Department of Genome Sciences at the University of Washington.
Keywords:
Software; knowledge base; mass spectrometry; targeted proteomics; SRM; MRM; chromatogram libraries; skyline