Near-Infrared Emitting Fluorescent BODIPY Nanovesicles for in Vivo Molecular Imaging and Drug Delivery

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• 作者：Li Quan ; Shi Liu ; Tingting Sun ; Xingang Guan ; Wenhai Lin ; Zhigang Xie ; Yubin Huang ; Yiqing Wang ; Xiabin Jing
• 刊名：ACS Applied Materials & Interfaces
• 出版年：2014
• 出版时间：September 24, 2014
• 年：2014
• 卷：6
• 期：18
• 页码：16166-16173
• 全文大小：453K
• ISSN：1944-8252

文摘

Near-infrared fluorescent nanovesicles were prepared by self-assembly of block copolymer hydrophilic poly(ethylene glycol) boron鈥揹ipyrromethenes in aqueous solution. The fluorescence enhancement induced by dissociation of nanovesicles could be used as a smart imaging and diagnostic tool. This nanovesicle could encapsulate the antitumor drug, and provide a powerful platform for imaging-guided tumor-specific drug delivery and therapy.

Keywords:

nanovesicles; near-infrared; BODIPY; in vivo imaging; drug delivery