Mechanistic Aspects of the Phosphine-Catalyzed Isomerization of Allenic Sulfones to 2-Arylsulfonyl 1,3-Dienes

详细信息    查看全文

• 作者：Carissa S. Hampton ; Michael Harmata
• 刊名：Journal of Organic Chemistry
• 出版年：2015
• 出版时间：December 18, 2015
• 年：2015
• 卷：80
• 期：24
• 页码：12151-12158
• 全文大小：491K
• ISSN：1520-6904

文摘

When an allenic sulfone is treated with a phosphine nucleophile and a proton shuttle, an isomerization to a 2-arylsulfonyl 1,3-diene occurs. Mechanistic aspects of the process were investigated leading to the formulation of a mechanism for the reaction. Some further optimization studies of this process are reported.