Copper(I)-Catalyzed Sulfonylation of 8-Aminoquinoline Amides with Sulfonyl Chlorides in Air

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• 作者：Huijie Qiao ; Suyan Sun ; Fan Yang ; Yu Zhu ; Weiguo Zhu ; Yaxi Dong ; Yusheng Wu ; Xiangtao Kong ; Ling Jiang ; Yangjie Wu
• 刊名：Organic Letters
• 出版年：2015
• 出版时间：December 18, 2015
• 年：2015
• 卷：17
• 期：24
• 页码：6086-6089
• 全文大小：368K
• ISSN：1523-7052

文摘

A simple and mild protocol for copper(I)-mediated sulfonylation of 8-aminoquinoline amides with sulfonyl chlorides was developed, affording desired products in moderate to good yields. This reaction proceeds in air and features excellent substrate tolerance, especially for aliphatic sulfonyl chlorides.