Metal-Free Approach for the Synthesis of N-Aryl Sulfoximines via Aryne Intermediate

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• 作者：Sravan Kumar Aithagani ; Saidulu Dara ; Gurunadham Munagala ; Hariprasad Aruri ; Mahipal Yadav ; Shweta Sharma ; Ram A. Vishwakarma ; Parvinder Pal Singh
• 刊名：Organic Letters
• 出版年：2015
• 出版时间：November 20, 2015
• 年：2015
• 卷：17
• 期：22
• 页码：5547-5549
• 全文大小：316K
• ISSN：1523-7052

文摘

A metal-free and operationally simple N-arylation of NH-sulfoximines with aryne precursors is reported. Transition metal-free reaction conditions and shorter reaction times are the highlights of the present method. The mild optimized condition was also found to be suitable with enantiopure substrates.