Human Body Burden and Dietary Methylmercury Intake: The Relationship in a Rice-Consuming Population

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• 作者：Ping Li ; Xinbin Feng ; Hing-Man Chan ; Xiaofeng Zhang ; Buyun Du
• 刊名：Environmental Science & Technology
• 出版年：2015
• 出版时间：August 18, 2015
• 年：2015
• 卷：49
• 期：16
• 页码：9682-9689
• 全文大小：353K
• ISSN：1520-5851

文摘

Rice can be the main route of methylmercury (MeHg) exposure for rice-consuming populations living in area where mercury (Hg) is mined. However, the current risk assessment paradigm for MeHg exposure is based on epidemiological data collected from fish-consuming populations. This study was designed to evaluate the relationship between dietary MeHg intake and human body burden in a rice -consuming population from the Wanshan Hg mining area in China. Hair MeHg concentrations averaged 2.07 卤 1.79 渭g/g, and the average blood MeHg concentration across the study area ranged from 2.20 to 9.36 渭g/L. MeHg constituted 52.8 卤 17.5% and 71.7 卤 18.2% of total Hg (THg) on average in blood and hair samples, respectively. Blood and hair MeHg concentrations, rather than THg, can be used as a proxy of human MeHg exposure. Hair MeHg levels showed no significant monthly variation; however, hair THg can be impacted by inorganic Hg exposure. The toxicokinetic model of MeHg exposure based on fish consumption underestimated the human hair MeHg levels, and this may be a consequence of the high hair-to-blood MeHg ratio (361 卤 105) in the studied rice-consuming population. The use of risk assessment models based on fish consumption may not be appropriate for inland mining areas where rice is the staple food.