Cd2+ Triggered the FRET 鈥淥N鈥? A New Molecular Switch for the Ratiometric Detection of Cd2+ with Live-Cell Imaging and Bound X-ray Structure

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• 作者：Krishnendu Aich ; Shyamaprosad Goswami ; Sangita Das ; Chitrangada Das Mukhopadhyay ; Ching Kheng Quah ; Hoong-Kun Fun
• 刊名：Inorganic Chemistry
• 出版年：2015
• 出版时间：August 3, 2015
• 年：2015
• 卷：54
• 期：15
• 页码：7309-7315
• 全文大小：411K
• ISSN：1520-510X

文摘

On the basis of the F枚rster resonance energy transfer mechanism between rhodamine and quinoline鈥揵enzothiazole conjugated dyad, a new colorimetric as well as fluorescence ratiometric probe was synthesized for the selective detection of Cd²⁺. The complex formation of the probe with Cd²⁺ was confirmed through Cd²⁺-bound single-crystal structure. Capability of the probe as imaging agent to detect the cellular uptake of Cd²⁺ was demonstrated here using living RAW cells.