Au Nanorods@NaGdF4/Yb3+,Er3+ Multifunctional Hybrid Nanocomposites with Upconversion Luminescence, Magnetism, and Photothermal Property

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• 作者：Yan Song ; Guixia Liu ; Xiangting Dong ; Jinxian Wang ; Wensheng Yu ; Jingmei Li
• 刊名：Journal of Physical Chemistry C
• 出版年：2015
• 出版时间：August 13, 2015
• 年：2015
• 卷：119
• 期：32
• 页码：18527-18536
• 全文大小：631K
• ISSN：1932-7455

文摘

Multifunctional nanomaterials possessing upconversion luminescence, magnetic, and photothermal properties show promising applications in biology and medicine. In this study, a new kind of luminescent-magnetic-thermal core鈥搒hell hybrid nanocomposite was fabricated combining rare earth Yb³⁺ and Er³⁺ ions doped NaGdF₄ nanocrystals as shell layer materials and gold nanorods (AuNRs) as cores. The structure, morphology, composition, and properties of the multifunctional hybrid nanocomposites were characterized by X-ray powder diffraction, transmission electron microscopy, energy dispersive spectroscopy, upconversion photoluminescence spectra, vibrating sample magnetometer, sensitive thermometer, and cytotoxicity assessment, respectively. The multifunctional hybrid nanocomposites have rodlike morphology and core鈥搒hell structure. The uniform NaGdF₄/Yb³⁺,Er³⁺ shell with a thickness of around 4.5 nm was coated on the surface of AuNRs with a length of 40 nm and a diameter of 12 nm. The AuNRs@NaGdF₄/Yb³⁺,Er³⁺ multifunctional nanocomposites provide an excellent upconversion emission under excitation at 980 nm and a superparamagnetic behavior with magnetic susceptibility of 8.0 脳 10^鈥? emu路g^鈥?路Oe^鈥? at 300 K and saturation magnetization value of 102 emu路g^鈥? at 2 K. More significantly, when AuNRs@NaGdF₄/Yb³⁺,Er³⁺ aqueous suspensions of 100 渭g路mL^鈥? were irradiated by a 980 nm NIR laser for 10 min, the temperature was significantly elevated to 48 掳C. At the same time, the temperature of photothermal transduction can be easily controlled by adjusting the concentration of nanocomposites. Preliminary investigation of incubating with HeLa cells displays that the multifunctional nanocomposites exhibit a good biocompatibility. Moreover, the nanocomposites may be effectively utilized for bioimaging and photothermal therapy in living cells.