Expedient and Divergent Tandem One-Pot Synthesis of Benz[e]indole and Spiro[indene-1,3鈥?pyrrole] Derivatives from Alkyne-Tethered Chalcones/Cinnamates and TosMIC

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• 作者：Xue Zhang ; Chengjie Feng ; Tao Jiang ; Yifei Li ; Ling Pan ; Xianxiu Xu
• 刊名：Organic Letters
• 出版年：2015
• 出版时间：July 17, 2015
• 年：2015
• 卷：17
• 期：14
• 页码：3576-3579
• 全文大小：407K
• ISSN：1523-7052

文摘

An efficient solvent-dependent regioselective [3 + 2]-cycloaddition/iodocyclization cascade reaction of alkyne-tethered chalcones/cinnamates and TosMIC has been developed. The reaction represents a novel protocol for the expedient and divergent one-pot synthesis of benz[e]indoles and spiro[indene-1,3鈥?pyrroles] from acyclic common precursors at room temperature.