Interplay between Static and Dynamic Energy Transfer in Biofunctional Upconversion Nanoplatforms

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• 作者：Yadan Ding ; Fei Wu ; Youlin Zhang ; Xiaomin Liu ; Elinore M. L. D. de Jong ; Tom Gregorkiewicz ; Xia Hong ; Yichun Liu ; Maurice C. G. Aalders ; Wybren Jan Buma ; Hong Zhang
• 刊名：The Journal of Physical Chemistry Letters
• 出版年：2015
• 出版时间：July 2, 2015
• 年：2015
• 卷：6
• 期：13
• 页码：2518-2523
• 全文大小：423K
• ISSN：1948-7185

文摘

Clarification of the energy-transfer (ET) mechanism is of vital importance for constructing efficient upconversion nanoplatforms for biological/biomedical applications. Yet, most strategies of optimizing these nanoplatforms were casually based on a dynamic ET assumption. In this work, we have modeled quantitatively the shell-thickness-dependent interplay between dynamic and static ET in nanosystems and validated the model in a typical biofunctional upconversion nanoplatform composed of NaYF₄:Er, Yb/NaYF₄ upconversion nanoparticles (UCNPs), and energy-acceptor photosensitizing molecule Rose Bengal (RB). It was determined that with a proper thickness shell, the energy transferred via dynamic ET as well as static ET in this case could be significantly improved by 鈭? and 鈭? fold, respectively, compared with the total energy transferred from bare core UCNPs. Our results shall form the bedrock in designing highly efficient ET-based biofunctional nanoplatforms.