Concentrations of Inorganic Arsenic in Milled Rice from China and Associated Dietary Exposure Assessment

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• 作者：Yatao Huang ; Min Wang ; Xuefei Mao ; Yongzhong Qian ; Tianjin Chen ; Ying Zhang
• 刊名：Journal of Agricultural and Food Chemistry
• 出版年：2015
• 出版时间：December 23, 2015
• 年：2015
• 卷：63
• 期：50
• 页码：10838-10845
• 全文大小：300K
• ISSN：1520-5118

文摘

Total arsenic (As) and inorganic As (As_i) in milled rice (n = 1653) collected from China were studied to evaluate the contamination level, distribution, and health risks. The mean concentrations of the total As and As_i were 116.5 and 90.9 μg/kg, respectively. There were significant differences (P < 0.01) between the 11 provinces, and 1.1% of samples exceeded the maximum contaminant level established by Chinese legislation. According to the exposure assessment method of probabilistic simulation, all values of the target hazard quotients (THQs) for chronic noncarcinogenic risks (skin lesions as the point of departure) were below 1, suggesting that the Chinese population will not encounter a significant noncarcinogenic risk. However, the mean values of margin of exposure (MOE) for lung cancer risks ranging from 3.86 to 8.54 were under 100 for all age groups and genders of the Chinese population; moreover, MOE values for some major rice-producing and -consuming countries, such as Japan, Thailand, Bangladesh, and the United States, were all also below 100. More attention should be paid to carcinogenic risks from rice As_i intake, and some control measures to reduce rice As_i intake should be taken.