Copper-Catalyzed Intermolecular Chloro- and Bromotrifluoromethylation of Alkenes

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• 作者：Mingyang Fu ; Long Chen ; Yongpeng Jiang ; Zhong-Xing Jiang ; Zhigang Yang
• 刊名：Organic Letters
• 出版年：2016
• 出版时间：February 5, 2016
• 年：2016
• 卷：18
• 期：3
• 页码：348-351
• 全文大小：427K
• ISSN：1523-7052

文摘

A highly practical copper-catalyzed intermolecular halotrifluoromethylation of alkenes has been developed under mild reaction conditions. A variety of Cl/Br-containing trifluoromethyl derivatives were directly synthesized from a wide range of alkenes, including electron-deficient and unactivated alkenes.