Graphene–Alumina Nanocomposites with Improved Mechanical Properties for Biomedical Applications

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• 作者：Jian Liu ; Yang Yang ; Hany Hassanin ; Neeraj Jumbu ; Sunan Deng ; Qian Zuo ; Kyle Jiang
• 刊名：ACS Applied Materials & Interfaces
• 出版年：2016
• 出版时间：February 3, 2016
• 年：2016
• 卷：8
• 期：4
• 页码：2607-2616
• 全文大小：615K
• ISSN：1944-8252

文摘

This paper presents a study on graphene platelet (GPL)-reinforced alumina (Al₂O₃) ceramic composites and the relationships between the loading of GPL and both mechanical properties and in vitro biocompatibility. Al₂O₃ powders with different GPL contents were prepared and sintered using a gas protected pressure-less furnace. The examination of the results shows the density of the composites varying from 99.2% to 95.6% with the loading of GPL from 0.75 to 1.48 vol %. Raman studies show that moderate agglomerations of GPLs occur during the ball milling process and graphitic defects were produced during the high temperature processing. Mechanical properties of the Al₂O₃ matrix are significantly improved by adding GPLs. A maximum increase of approximately 60% in flexural strength and 70% in fracture toughness are achieved by introducing 0.75 vol % GPLs. In the biocompatibility tests, it was found that cells directly seeding on top of GPL/Al₂O₃ samples showed better initial attachment (3 h after seeding) and viability (3 days after incubation) than the monolithic Al₂O₃, indicating that the GPL/Al₂O₃ composites have comparable or more favorable biocompatibility. The excellent mechanical and biomedical properties of the GPL/Al₂O₃ composites may enable them to be applied to a wide range of engineering and biomedical applications.