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Mimicking the Cell: Bio-Inspired Functions of Supramolecular Assemblies
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  • 作者:Yingfeng Tu ; Fei Peng ; Alaa Adawy ; Yongjun Men ; Loai K. E. A. Abdelmohsen ; Daniela A. Wilson
  • 刊名:Chemical Reviews
  • 出版年:2016
  • 出版时间:February 24, 2016
  • 年:2016
  • 卷:116
  • 期:4
  • 页码:2023-2078
  • 全文大小:3455K
  • 年卷期:

    Yingfeng Tu received his BSc Degree in Pharmacy from Wenzhou Medical University, China, in 2010 and a Master Degree in Pharmaceutical Science from Peking University in 2013. During the master’s program, he focused on drug delivery systems targeting brain tumors using multifunctional liposomal formulations. Currently he is a Ph.D. candidate in the Department of Bio-organic Chemistry at Radboud University, The Netherlands. His research is focused on self-propelled supramolecular motors with stimuli responsive valves for movement control and novel drug delivery.

    Fei Peng obtained her Master’s degree from Health Science Center, Peking University, China, in 2013. During her Master’s program (2010-2013), she carried out research on poly(amidoamine) dendrimers as a multifunctional drug delivery system. She is now a Ph.D. candidate at the Department of Bio-organic Chemistry, Radboud University, and a recipient of a scholarship from the China Scholarship Council. Her research interests concerns self-guided supramolecular polymeric nanomotors for drug delivery.

    Alaa Adawy obtained her Bachelor Degree in Biophysics with honours (top of the class) from Faculty of Science, Ain Shams University, Cairo, Egypt. After a first appointment as academic assistant at the Physics Department in the same faculty, with 28 h/week teaching tasks, and completion of her Medical Biophysics Master’s program in Biomaterials she was promoted to Assistant lecturer. In 2009, she relocated to Nijmegen, The Netherlands, and conducted her Ph.D. research on crystallization of biological macromolecules at the Institute for Molecules and Materials, Radboud University, under the supervision of Prof. Dr. Elias Vlieg, Prof. Dr. Willem de Grip, and Dr. Willem van Enckevort. Since 2014, she has been a postdoctoral fellow at the same institute. Alaa is interested in conducting research on interdisciplinary topics, and her current research focuses on crystallization in nanoconfined compartments.

    Yongjun Men received his Bachelor’s Degree in Chemistry in Zhengzhou University, China, in 2007, and his Master’s degree in Polymer Chemistry in Beijing Normal University, China, in 2011. Then, he moved to Max Planck Institute of Colloids and Interfaces, Germany, and completed his Ph.D. degree on a topic of poly(ionic liquid)-based thermoresponsive polymers and porous carbon materials under the supervision of Prof. Markus Antonietti and Dr Jiayin Yuan. At present, he is a postdoctoral researcher in the Department of Bio-organic Chemistry at Radboud University, The Netherlands. His current research focuses on the design of intelligent, self-propelled supramolecular assemblies as nanoengineered delivery systems.

    Loai K. Abdelmohsen received his B. Sc. Degree in Chemistry and Microbiology from Alexandria University, Egypt. He completed his Master’s degree at Radboud University, The Netherlands, in the Departments of Bio-organic and Physical Organic Chemistry. He is currently a Ph.D. student in the department of Bio-organic Chemistry at Radboud University. His current research focuses on designing new biocompatible nanomotor systems that utilize natural substrates for their propulsion.

    Daniela A. Wilson (born Apreutesei) received her B.Sc. degree (Hon) in chemistry from “A. I. Cuza” University of Iasi, Romania, in 2001, and an M.S. degree (Hon) in environmental chemistry from the same university in 2003. In 2006, she received her Ph.D. with distinction “summa cum laudae” from “Gh. Asachi” Technical University of Iasi, Romania. During her Ph.D. she obtained two fellowships in Japan and the U.K. as an exchange Ph.D. student and Marie Curie fellow. She then worked as a postdoctoral researcher at University of Pennsylvania, Philadelphia, USA, and Radboud University Nijmegen, Netherlands, in the groups of Prof. Virgil Percec and Prof. Roeland Nolte on several topics in synthetic organic chemistry, organometallic chemistry, and supramolecular and polymer chemistry. In 2012, she was awarded an ERC starting grant to investigate nanomotors with autonomous propulsion in biological systems. She is currently assistant professor at the Institute for Molecules and Materials, Radboud University. Her research interests span a broad range of topics at the interface of supramolecular chemistry, macromolecular chemistry, and nanotechnology.
  • ISSN:1520-6890
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