Additive Effects on Asymmetric Catalysis

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• 作者：Liang Hong ; Wangsheng Sun ; Dongxu Yang ; Guofeng Li ; Rui Wang
• 刊名：Chemical Reviews
• 出版年：2016
• 出版时间：March 23, 2016
• 年：2016
• 卷：116
• 期：6
• 页码：4006-4123
• 全文大小：7726K
• 年卷期：Liang Hong was born in 1983 in Jiangsu Province, China, and received his B.Sc. degree in Biology from Lanzhou University in 2007. After he obtained his Ph.D. degree under the supervision of Professor Rui Wang in 2011 in the same university, he joined Professor Wang’s group as an assistant professor. His research interests cover asymmetric catalysis, synthetic methodology, as well as medicinal chemistry.
  Wangsheng Sun was born in 1987 in Gansu Province, China, and received his B.Sc. degree in Biology from Lanzhou University in 2009. He obtained his Ph.D. degree under the supervision of Professor Rui Wang in the same university in 2014. His research interests cover asymmetric catalysis, synthetic methodology, as well as medicinal chemistry.
  Dongxu Yang was born in 1986 in Liaoning Province, China. After receiving his B.S. degree from Lanzhou University in 2009, he joined the research group of Professor Rui Wang to pursue his Ph.D. degree in the same university. After receiving his Ph.D. degree in 2015, he joined the research group of Professor Rui Wang as an assistant professor, working on chiral drugs design and asymmetric synthesis.
  Guofeng Li was born in Shanxi, China, in 1990. He received his B.S. degree in Biotechnology from Lanzhou University in 2013. He is currently a graduate student under the direction of Professor Rui Wang at the Lanzhou University as a Ph.D. student. His studies focus on organic asymmetric catalysis.
  Rui Wang (1963) received his Ph.D. degree in Organic Chemistry and Medicinal Chemistry in 1988 from the Sino–Japan joint Ph.D. program of Lanzhou University and Kyoto University, Japan. He then worked as a postdoctoral fellow in Lanzhou University and the University of Kansas from 1989 to 1993. He was appointed as a professor at Lanzhou University in 1994, and his interests mainly focus on asymmetric catalysis and peptide chemistry, biology, and pharmaceutical sciences. He has received a number of distinctions including the Cheung Kong Professorship in 2004, the Outstanding Young Scientist Award of the National Natural Science Foundation of China in 2005, the Thomson Reuters Research Fronts Award in 2008, the State Natural Science Award (2nd class) in 2009, the Science and Technology Award (1st class) of the Chinese Pharmaceutical Association in 2013, and the Natural Science Award (1st class) of the Ministry of Education of China in 2013.
• ISSN：1520-6890

文摘

This review highlights a number of additives that can be used to make asymmetric reactions perfect. Without changing other reaction conditions, simply adding additives can lead to improved asymmetric catalysis, such as reduced reaction time, improved yield, or/and increased selectivity.