PPh3O as an Activating Reagent for One-Pot Stereoselective Syntheses of Di- and Polybrominated Esters from Simple Aldehydes

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• 作者：Tian-Yang Yu ; Hao Wei ; Yong-Chun Luo ; Yao Wang ; Zhu-Yin Wang ; Peng-Fei Xu
• 刊名：Journal of Organic Chemistry
• 出版年：2016
• 出版时间：April 1, 2016
• 年：2016
• 卷：81
• 期：7
• 页码：2730-2736
• 全文大小：468K
• ISSN：1520-6904

文摘

An efficient one-pot method for the syntheses of di- and polybrominated esters from readily available aldehydes is reported. The direct use of the in situ generated byproduct PPh₃O in the following reactions greatly improves the efficiency of the cascade. Also, the substrate scope of the reaction is proved to be broad.