Diastereoselective 1,3-Dipolar Cycloadditions of N,N‿Cyclic Azomethine Imines with Iminooxindoles for Access to Oxindole Spiro-N,N-bicyclic Heterocycles

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• 作者：Hong-Wu Zhao ; Bo Li ; Hai-Liang Pang ; Ting Tian ; Xiao-Qin Chen ; Xiu-Qing Song ; Wei Meng ; Zhao Yang ; Yu-Di Zhao ; Yue-Yang Liu
• 刊名：Organic Letters
• 出版年：2016
• 出版时间：February 19, 2016
• 年：2016
• 卷：18
• 期：4
• 页码：848-851
• 全文大小：288K
• ISSN：1523-7052

文摘

In the presence of CuI, 1,3-dipolar cycloadditions of N,N′-cyclic azomethine imines with iminooxindoles proceeded readily and furnished novel oxindole spiro-N,N-bicyclic heterocycles in moderate to excellent chemical yields with excellent diastereoselectivities.