Cu-Catalyzed C–H Trifluoromethylation of 3-Arylprop-1-ynes for the Selective Construction of Allenic Csp2–CF3 and Propargyl Csp3–CF3 Bonds

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• 作者：Yun-Long Ji ; Jia-Jia Luo ; Jin-Hong Lin ; Ji-Chang Xiao ; Yu-Cheng Gu
• 刊名：Organic Letters
• 出版年：2016
• 出版时间：March 4, 2016
• 年：2016
• 卷：18
• 期：5
• 页码：1000-1003
• 全文大小：318K
• ISSN：1523-7052

文摘

A new method has been developed for the Cu-catalyzed C–H trifluoromethylation of 3-arylprop-1-ynes for the selective construction of allenic Csp²–CF₃ and propargyl Csp³–CF₃ bonds. The selective formation of allenic Csp²–CF₃ and propargyl Csp³–CF₃ bonds can be controlled by modifying the reaction conditions.