Microwave-Assisted, Metal-Free, Base-Mediated C–N Bond Formation/Cleavage: Synthesis of Benzimidazo[1,2-a]quinazoline Derivatives

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• 作者：Prashant Kumar ; Anil K. Singh ; Vijay Bahadur ; Christophe Len ; Nigel G. J. Richards ; Virinder S. Parmar ; Erik V. Van der Eycken ; Brajendra K. Singh
• 刊名：ACS Sustainable Chemistry & Engineering
• 出版年：2016
• 出版时间：April 4, 2016
• 年：2016
• 卷：4
• 期：4
• 页码：2206-2210
• 全文大小：341K
• ISSN：2168-0485

文摘

A novel, rapid, and efficient microwave-assisted, metal-free, base-mediated approach has been developed for the construction of benzimidazo[1,2-a]quinazolines from readily available building blocks. This synthetic strategy affords a diverse range of benzimidazo[1,2-a]quinazoline derivatives in moderate to good yields.