Dramatically Promoted Swelling of a Hydrogel by Pillar[6]arene–Ferrocene Complexation with Multistimuli Responsiveness

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• 作者：Mengfei Ni ; Ning Zhang ; Wei Xia ; Xuan Wu ; Chenhao Yao ; Xin Liu ; Xiao-Yu Hu ; Chen Lin ; Leyong Wang
• 刊名：Journal of the American Chemical Society
• 出版年：2016
• 出版时间：May 25, 2016
• 年：2016
• 卷：138
• 期：20
• 页码：6643-6649
• 全文大小：455K
• 年卷期：0
• ISSN：1520-5126

文摘

The swelling–shrinking transition of hydrogels is crucial for their wide applications such as actuators and drug delivery. We hereby fabricated a smart hydrogel with ferrocene groups on pendant of polymer networks. While it was immersed in the water-soluble pillar[6]arene (WP6) aqueous solution, the hydrogel was dramatically swollen, which was an approximately 11-fold promotion in weight compared with that in pure water, due to the formation of the inclusion complexes between WP6 and ferrocene groups in the hydrogel. In particular, the well-swollen hydrogel exhibited good responsiveness to multistimuli including temperature, pH, redox, and competitive guests by tuning the dissociation/formation of WP6–ferrocene inclusion complexes or the strength of their charges. Meanwhile, potential application of such a smart hydrogel in pH-responsive drug release was demonstrated as well.