Preparing (Multi)Fluoroarenes as Building Blocks for Synthesis: Nickel-Catalyzed Borylation of Polyfluoroarenes via C–F Bond Cleavage

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• 作者：Jing Zhou ; Maximilian W. Kuntze-Fechner ; Rüdiger Bertermann ; Ursula S. D. Paul ; Johannes H. J. Berthel ; Alexandra Friedrich ; Zhenting Du ; Todd B. Marder ; Udo Radius
• 刊名：Journal of the American Chemical Society
• 出版年：2016
• 出版时间：April 27, 2016
• 年：2016
• 卷：138
• 期：16
• 页码：5250-5253
• 全文大小：289K
• 年卷期：0
• ISSN：1520-5126

文摘

The [Ni(IMes)₂]-catalyzed transformation of fluoroarenes into arylboronic acid pinacol esters via C–F bond activation and transmetalation with bis(pinacolato)diboron (B₂pin₂) is reported. Various partially fluorinated arenes with different degrees of fluorination were converted into their corresponding boronate esters.