Visible Light Induced Oxydifluoromethylation of Styrenes with Difluoromethyltriphenylphosphonium Bromide

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• 作者：Yang Ran ; Qing-Yu Lin ; Xiu-Hua Xu ; Feng-Ling Qing
• 刊名：Journal of Organic Chemistry
• 出版年：2016
• 出版时间：August 19, 2016
• 年：2016
• 卷：81
• 期：16
• 页码：7001-7007
• 全文大小：422K
• 年卷期：0
• ISSN：1520-6904

文摘

A convenient, visible light induced oxidifluoromethylation of styrenes was developed. This protocol employs the readily prepared difluoromethyltriphenylphosphonium bromide as the difluoromethylating reagent and alcohols/water as the nucleophiles, affording difluoromethyl(CF₂H)-containing alcohols and ethers in moderate to excellent yields.