In Vivo Self-Powered Wireless Cardiac Monitoring via Implantable Triboelectric Nanogenerator

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• 作者：Qiang Zheng ; Hao Zhang ; Bojing Shi ; Xiang Xue ; Zhuo Liu ; Yiming Jin ; Ye Ma ; Yang Zou ; Xinxin Wang ; Zhao An ; Wei Tang ; Wei Zhang ; Fan Yang ; Yang Liu ; Xilong Lang ; Zhiyun Xu ; Zhou Li ; Zhong Lin Wang
• 刊名：ACS Nano
• 出版年：2016
• 出版时间：July 26, 2016
• 年：2016
• 卷：10
• 期：7
• 页码：6510-6518
• 全文大小：663K
• 年卷期：0
• ISSN：1936-086X

文摘

Harvesting biomechanical energy in vivo is an important route in obtaining sustainable electric energy for powering implantable medical devices. Here, we demonstrate an innovative implantable triboelectric nanogenerator (iTENG) for in vivo biomechanical energy harvesting. Driven by the heartbeat of adult swine, the output voltage and the corresponding current were improved by factors of 3.5 and 25, respectively, compared with the reported in vivo output performance of biomechanical energy conversion devices. In addition, the in vivo evaluation of the iTENG was demonstrated for over 72 h of implantation, during which the iTENG generated electricity continuously in the active animal. Due to its excellent in vivo performance, a self-powered wireless transmission system was fabricated for real-time wireless cardiac monitoring. Given its outstanding in vivo output and stability, iTENG can be applied not only to power implantable medical devices but also possibly to fabricate a self-powered, wireless healthcare monitoring system.