Reductive C(sp2)–N Elimination from Isolated Pd(IV) Amido Aryl Complexes Prepared Using H2O2 as Oxidant

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• 作者：Elikplim Abada ; Peter Y. Zavalij ; Andrei N. Vedernikov
• 刊名：Journal of the American Chemical Society
• 出版年：2017
• 出版时间：January 18, 2017
• 年：2017
• 卷：139
• 期：2
• 页码：643-646
• 全文大小：316K
• ISSN：1520-5126

文摘

Di-2-pyridyl ketone (dpk)-supported amidoarylpallada(II)cycles derived from various 2-(N-R-amino)biphenyls (R = H, Me, CF₃CO, MeSO₂, CF₃SO₂) react with hydrogen peroxide in MeOH, THF, MeCN or AcOH to form the corresponding C–N coupled products, N-R-substituted carbazoles, in 82–98% yield. For R = MeSO₂ and CF₃SO₂, the corresponding reaction intermediates, amidoaryl Pd(IV) complexes were isolated and characterized by single crystal X-ray diffraction and/or NMR spectroscopy. For the first time, the C(sp²)–N reductive elimination from isolated amidoaryl Pd(IV) complexes has been studied in detail.